TSH
TSH is a hormone that controls the thyroid and plays a central role in your metabolism and energy balance.
Summary
What is TSH?
TSH stands for thyroid-stimulating hormone. This hormone is produced by the pituitary gland, a small gland at the base of the brain that acts as the conductor of a large part of your endocrine system.
The task of TSH is clear: it instructs the thyroid gland to produce the hormones thyroxine (T4) and triiodothyronine (T3). These thyroid hormones, in turn, regulate numerous bodily processes, including your metabolism, energy balance, and thermoregulation. You can think of TSH as a switch that turns the activity of the thyroid gland on or off.
There is a precise feedback mechanism between the pituitary gland and the thyroid gland. If sufficient T3 and T4 are circulating in the blood, the pituitary gland reduces TSH production. If thyroid hormone levels are too low, the pituitary gland increases TSH production to encourage the thyroid to work harder.
Why is TSH measured?
Measuring TSH in the blood is one of the most commonly used methods to assess thyroid function. Doctors use this test for symptoms that may indicate a disturbed thyroid function, but also as a check-up for people who already have a thyroid condition and are being treated for it.
Typical symptoms for which a TSH determination can be useful include persistent fatigue, unexplained weight changes, feeling cold or excessive sweating, palpitations, mood swings, or concentration problems. Because these symptoms also occur in many other conditions, the TSH value helps the doctor to search more specifically for a cause.
In addition, TSH is regularly measured during fertility testing. A properly functioning thyroid is important for a regular menstrual cycle and a healthy pregnancy. TSH is also checked periodically in people taking thyroid medication to assess whether the dosage is still appropriate.
What do abnormal TSH values mean?
An abnormal TSH value tells you something about the balance between the pituitary gland and the thyroid gland. It is important to realize that a single abnormal result must always be assessed in context, together with other symptoms and possibly additional blood values such as free T3 and free T4.
High TSH value
An elevated TSH value means that the pituitary gland is working extra hard to get the thyroid gland functioning. This indicates that the thyroid gland itself is producing too few hormones. Doctors call this hypothyroidism, or an underactive thyroid.
Symptoms associated with this include fatigue, weight gain, a slow heart rate, feeling cold, dry skin, and sometimes depressive feelings. Hypothyroidism is easily treatable with thyroid hormone in tablet form.
Low TSH value
A reduced TSH value indicates that the pituitary gland is producing less TSH because there is already too much thyroid hormone present in the blood. This can be a sign of hyperthyroidism, an overactive thyroid.
With an overactive thyroid, symptoms such as palpitations, unwanted weight loss, nervousness, sleep problems, and increased sweating may occur. A TSH that is too low also requires further diagnostic testing and guidance by a doctor.
When is it advisable to have TSH measured?
Having TSH measured is advisable when you experience long-term symptoms that may be related to a thyroid disorder. Think of persistent fatigue for which there is no clear explanation, or changes in your weight, mood, or heart rhythm without an identifiable reason.
It can also be useful to have your TSH level checked if you have a family history of thyroid disorders, if you have an autoimmune disease, or if you want to become pregnant or are already pregnant. Thyroid problems are more common than many people think and sometimes remain undetected for a long time because the symptoms develop gradually.
At Zample, you can easily request a blood test to determine TSH. The result provides you and your doctor with a clear starting point for further assessment. Abnormal values do not automatically mean that something serious is wrong, but they do warrant further investigation and, if necessary, timely action.
Author
The team at zample™